SBRC Analytics
The SBRC has two main suites of analytical equipment mainly composed of HPLC and GC-MS systems. These range from in-line gas analysers to monitor fermentation systems in real time to highly specialist LC-MS capable of co-identifying and quantifying large numbers of analytes and metabolites.
The equipment is managed and operated by a dedicated and specialist team of technical staff.
Specific items of equipment include:
- GC and GC-MS Systems
- HPLC and UHPLC Systems
- UHPLC-(Orbitrap) MS/MS
- Waters Q-ToF Premier LC-MS/MS
- Triple Quadrupole LC-MS/MS Systems
- Thermo Trace 1310 and Focus
- Agilent 6890 + MSD
- Routine compound quantitation in culture supernatant headspace samples
Thermo Trace 1310
- Thermo Ultimate 3000 and Perkin-Elmer 200
- Routine high throughput compound quantitation in culture supernatants
- Flexible systems with:
- Various modes and scales
- Binary/quaternary phase
- UV, Diode Array and RI detection
- Autosamplers
- MS inlets
Perkin-Elmer 200
Thermo Ultimate 3000
Thermo QExactive-Plus
- High throughput multiplex comprehensive metabolomics
- 1ppm mass accuracy enables unambiguous identifications
- Intracellular and culture supernatant analyses using stable isotope standardisation
Thermo QExactive-Plus
- Routine compound ID and target assay development
- 10ppm Mass accuracy
Waters Q-ToF Premier
- Waters Quattro-LC and Quattro-Ultima
- Routine high throughput quantitation of compounds in intracellular and culture supernatant samples
- High sensitivity and dynamic range
Waters Quattro-LC
Waters Quattro-Ultima