Professor Eriko Takano
Professor Eriko Takano

Professor Eriko Takano

Professor Eriko Takano is currently Professor of Synthetic Biology at the University of Manchester, School of Chemistry, Faculty of Science and Engineering, Manchester Institute of Biotechnology. Until July 2016, she was in the Faculty of Life Sciences which she joined in 2012. In 2014, she was appointed as the Biotechnology and Synthetic Biology Research Theme Director of the Faculty and director for the newly funded SYNBIOCHEM, BBSRC-EPSRC Synthetic Biology Research Centre, SYNBIOCHEM, at the University of Manchester. She has an internationally leading position in synthetic biology of antibiotic production. Her interests are in bioinformatics software development for designing natural products producers (e.g. antiSMASH); untargeted metabolomics for chassis engineering in Streptomyces; secondary metabolite biosynthesis pathway assembly;and regulatory circuits engineering through signalling molecules and noncoding RNAs. She has published 78 peer-reviewed papers since 1993 (h-index 34), as well as 3 book chapters and 3 patents. Present and past funding sources include BBSRC, ERA-IB, TSB, H2020, STW (the Dutch Research Agency, Technology Foundation), NWO (The Netherlands Organisation for Scientific Research), BE-Basic, EraSysBio SysMO-STREAM, EUFP6 ActinoGEN, DFG, with a total current funding of more than £3M. Eriko has been awarded the Rosalind Franklin Fellowship from the University of Groningen (2006), Naito Kinen Kaigai Ryigaku Jyoseikin from the Naito Foundation Japan (1994), and the Lepetit Award from Lepetit and the Italian Society for General Microbiology and Microbial Biotechnology (1993). She was an expert advisor for the European Commission Scientific Committee on Emerging and Newly Identified Health Risks on synthetic biology, where she contributed to series of three official Opinions with major impact on the development of the field. For more information see http://synbiochem.co.uk/

Recent publications:

  1. Carbonell P, Currin A, Jervis AJ, Rattray NJW, Swainston N, Yan C, Takano E, Breitling: Bioinformatics for the synthetic biology of natural products: Integrating across the Design–Build–Test cycle. Nat. Prod. Rep. (2016) 33:925-932.

  2. Medema MH, Kottmann R, Yilmaz P, Cummings M, [146 co-authors in alphabetical order], Breitling R, Takano E, Glöckner FO (2015): The Minimum Information about a Biosynthetic Gene cluster (MIBiG) specification. Nature Chem. Biol. (2015) 11: 625-631.

  3. Weber T, Blin K, Duddela S, Krug D, Kim HU, Bruccoleri R, Lee SY, Fischbach MA, Müller R, Wohlleben W, Breitling R, Takano E, Medema MH. antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clusters. Nucl. Acids Res. (2015) PMID:25948579.

  4. Diez V, Loznik M, Taylor S, Winn M, Rattray NJW, Podmore H, Micklefield J, GoodacreJ, Medema MH, Müller U, Bovenberg R, Janssen DB, Takano E. Functional exchangeability of oxidase and dehydrogenase reactions in the biosynthesis of hydroxyphenylglycine, a non-ribosomal peptide building block. ACS Synth Biol (2015) 4:796–807

  5. Breitling R, Takano E, Gardner TS. Judging synthetic biology risks. Science (2015) 347:107.

  6. Medema MH, Breitling R, Bovenberg RAL, and Takano E. Exploiting Plug-and-Play Synthetic Biology for Drug Discovery and Production in Microbes. Nature Rev Microbiol (2011) 9:131–137.

Contact

eriko.takano@manchester.ac.uk


Staff

  • Prof Nigel Minton
  • Alan Burbidge
  • Klaus Winzer
  • Dr Ying Zhang
  • Prof Pete Licence
  • Prof Jon Garibaldi
  • Dr Jamie Twycross
  • Prof Brigette Nerlich
  • Prof Jon King
  • Prof Greg Tucker
  • Prof Cameron Alexander
  • Prof Dave Barratt
  • Prof Charlie Hodgman
  • Dr Stephen Heeb
  • Louise Dynes